hi.. i don't know if you have ever visited any other forums but there is beginning to be quite a large number of us with this awful problem the rhuemy will tell you htat now you have arthritis .. hmmmm all my test were negative.. and that you need more remicade! don't do it.. my life is destroyed now.. i can no longer work ..the pain that i live with is completley disabling.. good luck i am currently seeking answers at a major medical institution that is studying the side effect of remicade...